Senior Expert Scientist

Senior Expert Scientist

My client is an innovating, dynamic and niche international privately-owned biopharma company currently expanding their Drug Discovery team in Switzerland, Lausanne area. Due to this growth my client is looking for a Senior Expert Scientist Drug Discovery to join their Translational Medicine team.


Responsibilities :

Ø Work in a matrix organization in close collaboration with other Translational Medicine functions (DMPK, Preclinical Safety and Diagnostics/Personalized Medicine) to characterize the pharmacological properties of our drug candidates

Ø Represents the Translational Pharmacology function in the Translational Medicine Project Teams May represent the Translational Medicine function in the global Project Teams and lead a Translational Medicine Project Team (core team member).

Ø Manages laboratory-to-human research in Contract Research Organizations: designs, monitors, and reports the primary and secondary pharmacology studies performed

Ø In vitro/in vivo pharmacology compounds selection and profiling, including off target characterization Proof of concept in vivo studies – PK/PD

Ø Identification, method development/validation of clinical pharmacodynamic (PDy) biomarkers Defines and manages the clinical translational PDy analyses (incl. blood and tissue biomarkers), data analyses and reporting according to GCPs and GCLPs

Ø Supports and advises the Clinical Research and Development team

Ø Contributes to the preparation of the pharmacology regulatory documentation (IDB, summaries for IND and IMPD, briefing documentation)

Ø May participate in interactions with Health Authorities.


Your profile :


Ø PhD in relevant expertise area or equivalent in biomedical engineering

Ø Minimum 5 years of experience in Translational Pharmacology Research and drug development Experience working in oncology projects is a must

Ø Experience in the pharma industry

Ø In-depth knowledge in translational research in personalized oncology and basic knowledge of related disciplines including histopathology, bioanalytics, pharmacokinetics and PK/PD

Ø Project management experience and strong communication and presentation skills

Ø Fluent in English