Senior Expert Scientist
My client is an innovating, dynamic and niche international privately-owned biopharma company currently expanding their Drug Discovery team in Switzerland, Lausanne area. Due to this growth my client is looking for a Senior Expert Scientist Drug Discovery to join their Translational Medicine team.
Responsibilities :
Ø Work in a matrix organization in close collaboration with other Translational Medicine functions (DMPK, Preclinical Safety and Diagnostics/Personalized Medicine) to characterize the pharmacological properties of our drug candidates
Ø Represents the Translational Pharmacology function in the Translational Medicine Project Teams May represent the Translational Medicine function in the global Project Teams and lead a Translational Medicine Project Team (core team member).
Ø Manages laboratory-to-human research in Contract Research Organizations: designs, monitors, and reports the primary and secondary pharmacology studies performed
Ø In vitro/in vivo pharmacology compounds selection and profiling, including off target characterization Proof of concept in vivo studies – PK/PD
Ø Identification, method development/validation of clinical pharmacodynamic (PDy) biomarkers Defines and manages the clinical translational PDy analyses (incl. blood and tissue biomarkers), data analyses and reporting according to GCPs and GCLPs
Ø Supports and advises the Clinical Research and Development team
Ø Contributes to the preparation of the pharmacology regulatory documentation (IDB, summaries for IND and IMPD, briefing documentation)
Ø May participate in interactions with Health Authorities.
Your profile :
Ø PhD in relevant expertise area or equivalent in biomedical engineering
Ø Minimum 5 years of experience in Translational Pharmacology Research and drug development Experience working in oncology projects is a must
Ø Experience in the pharma industry
Ø In-depth knowledge in translational research in personalized oncology and basic knowledge of related disciplines including histopathology, bioanalytics, pharmacokinetics and PK/PD
Ø Project management experience and strong communication and presentation skills
Ø Fluent in English
